Wednesday, October 3, 2012

October 3 Update

Pavel continues with his work to sort out the complicated signaling pathways used by FGFR3 in cartilage cells. 

Yuan and Jorge are at work optimizing the drug screening assay Pavel and I developed for a 384 well plate format.  We have done it before, by hand, in 96 well plates to screen 5,000 compounds.  We are going to screen 90,000+ this time using robots.  We have to use smaller volumes to make the screen affordable.  Converting from 96 wells to 384 wells sounds simple, but there is a lot of troubleshooting to do before we do the screen.

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